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Down-regulation of frizzled-7 expression decreases survival, invasion and metastatic capabilities of colon cancer cells

BACKGROUND: The canonical Wnt signalling pathway is activated in most sporadic colorectal cancers (CRCs). We previously reported that FZD7 functions as a receptor for the canonical Wnt signalling pathway in colon cancer cells. METHODS AND RESULTS: In this study, we examined the function of FZD7 in s...

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Detalles Bibliográficos
Autores principales:	Ueno, K, Hazama, S, Mitomori, S, Nishioka, M, Suehiro, Y, Hirata, H, Oka, M, Imai, K, Dahiya, R, Hinoda, Y
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2009
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768449/ https://www.ncbi.nlm.nih.gov/pubmed/19773752 http://dx.doi.org/10.1038/sj.bjc.6605307

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