Imaging metastatic bone disease from carcinoma of the prostate

Imaging bone metastases from prostate cancer presents several challenges. The lesions are usually sclerotic and appear late on the conventional X-ray. Bone scintigraphy is the mainstay of lesion detection, but is often not suitable for assessment of treatment response, particularly because of a ‘fla...

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Autores principales: Messiou, C, Cook, G, deSouza, N M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768452/
https://www.ncbi.nlm.nih.gov/pubmed/19789531
http://dx.doi.org/10.1038/sj.bjc.6605334
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author Messiou, C
Cook, G
deSouza, N M
author_facet Messiou, C
Cook, G
deSouza, N M
author_sort Messiou, C
collection PubMed
description Imaging bone metastases from prostate cancer presents several challenges. The lesions are usually sclerotic and appear late on the conventional X-ray. Bone scintigraphy is the mainstay of lesion detection, but is often not suitable for assessment of treatment response, particularly because of a ‘flare’ phenomenon after therapy. Magnetic resonance imaging is increasingly used in assessment, and newer techniques allow quantitation. In addition to (18)F-fluorodeoxyglucose ((18)FDG), newer PET isotopes are also showing promise in lesion detection and response assessment. This article reviews the available imaging modalities for evaluating prostatic bony metastases, and links them to the underlying pathological changes within bone lesions.
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spelling pubmed-27684522010-10-20 Imaging metastatic bone disease from carcinoma of the prostate Messiou, C Cook, G deSouza, N M Br J Cancer Minireview Imaging bone metastases from prostate cancer presents several challenges. The lesions are usually sclerotic and appear late on the conventional X-ray. Bone scintigraphy is the mainstay of lesion detection, but is often not suitable for assessment of treatment response, particularly because of a ‘flare’ phenomenon after therapy. Magnetic resonance imaging is increasingly used in assessment, and newer techniques allow quantitation. In addition to (18)F-fluorodeoxyglucose ((18)FDG), newer PET isotopes are also showing promise in lesion detection and response assessment. This article reviews the available imaging modalities for evaluating prostatic bony metastases, and links them to the underlying pathological changes within bone lesions. Nature Publishing Group 2009-10-20 2009-09-29 /pmc/articles/PMC2768452/ /pubmed/19789531 http://dx.doi.org/10.1038/sj.bjc.6605334 Text en Copyright © 2009 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Minireview
Messiou, C
Cook, G
deSouza, N M
Imaging metastatic bone disease from carcinoma of the prostate
title Imaging metastatic bone disease from carcinoma of the prostate
title_full Imaging metastatic bone disease from carcinoma of the prostate
title_fullStr Imaging metastatic bone disease from carcinoma of the prostate
title_full_unstemmed Imaging metastatic bone disease from carcinoma of the prostate
title_short Imaging metastatic bone disease from carcinoma of the prostate
title_sort imaging metastatic bone disease from carcinoma of the prostate
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768452/
https://www.ncbi.nlm.nih.gov/pubmed/19789531
http://dx.doi.org/10.1038/sj.bjc.6605334
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