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HIPK2 modulates p53 activity towards pro-apoptotic transcription
BACKGROUND: Activation of p53-mediated gene transcription is a critical cellular response to DNA damage and involves a phosphorylation-acetylation cascade of p53. The discovery of differences in the response to different agents raises the question whether some of the p53 oncosuppressor functions mig...
Autores principales: | Puca, Rosa, Nardinocchi, Lavinia, Sacchi, Ada, Rechavi, Gideon, Givol, David, D'Orazi, Gabriella |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768676/ https://www.ncbi.nlm.nih.gov/pubmed/19828042 http://dx.doi.org/10.1186/1476-4598-8-85 |
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