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Development of monoclonal antibodies and quantitative ELISAs targeting insulin-degrading enzyme

BACKGROUND: Insulin-degrading enzyme (IDE) is a widely studied zinc-metalloprotease implicated in the pathogenesis of type 2 diabetes mellitus, Alzheimer disease (AD) and varicella zoster virus infection. Despite more than six decades of research on IDE, progress has been hampered by the lack of wel...

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Detalles Bibliográficos
Autores principales:	DelleDonne, Anthony, Kouri, Naomi, Reinstatler, Lael, Sahara, Tomoko, Li, Lilin, Zhao, Ji, Dickson, Dennis W, Ertekin-Taner, Nilufer, Leissring, Malcolm A
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768702/ https://www.ncbi.nlm.nih.gov/pubmed/19835587 http://dx.doi.org/10.1186/1750-1326-4-39

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