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DNA damage induced by cis- and carboplatin as indicator for in vitro sensitivity of ovarian carcinoma cells

BACKGROUND: The DNA damage by platinum cytostatics is thought to be the main cause of their cytotoxicity. Therefore the measurement of the DNA damage induced by cis- and carboplatin should reflect the sensitivity of cancer cells toward the platinum chemotherapeutics. METHODS: DNA damage induced by c...

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Detalles Bibliográficos
Autores principales: Unger, Florian T, Klasen, Hermann A, Tchartchian, Garri, de Wilde, Rudy L, Witte, Irene
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768745/
https://www.ncbi.nlm.nih.gov/pubmed/19818145
http://dx.doi.org/10.1186/1471-2407-9-359

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