Cargando…

Inducible Costimulator Expression Regulates the Magnitude of Th2-Mediated Airway Inflammation by Regulating the Number of Th2 Cells

BACKGROUND: Inducible Costimulator (ICOS) is an important regulator of Th2 lymphocyte function and a potential immunotherapeutic target for allergy and asthma. A SNP in the ICOS 5′ promoter in humans is associated with increased atopy and serum IgE in a founder population and increased ICOS surface...

Descripción completa

Detalles Bibliográficos
Autores principales:	Clay, Bryan S., Shilling, Rebecca A., Bandukwala, Hozefa S., Moore, Tamson V., Cannon, Judy L., Welcher, Andrew A., Weinstock, Joel V., Sperling, Anne I.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768787/ https://www.ncbi.nlm.nih.gov/pubmed/19888475 http://dx.doi.org/10.1371/journal.pone.0007525

Ejemplares similares

Signaling through FcγRIII is required for optimal T helper type (Th)2 responses and Th2-mediated airway inflammation
por: Bandukwala, Hozefa S., et al.
Publicado: (2007)

Fas-positive T cells regulate the resolution of airway inflammation in a murine model of asthma
por: Tong, Jiankun, et al.
Publicado: (2006)

Protective Effector Memory CD4 T Cells Depend on ICOS for Survival
por: Moore, Tamson V., et al.
Publicado: (2011)

ICOS-Expressing Lymphocytes Promote Resolution of CD8-Mediated Lung Injury in a Mouse Model of Lung Rejection
por: Wu, Qiang, et al.
Publicado: (2013)

Costimulation through B7-2 (CD86) Is Required for the Induction of a Lung Mucosal T Helper Cell 2 (TH2) Immune Response and Altered Airway Responsiveness
por: Tsuyuki, Shogo, et al.
Publicado: (1997)

Regulation of Nasal Airway Homeostasis and Inflammation in Mice by SHP-1 and Th2/Th1 Signaling Pathways
por: Cho, Seok Hyun, et al.
Publicado: (2014)

The Contribution of Allergen-Specific IgG to the Development of Th2-Mediated Airway Inflammation
por: Williams, Jesse W., et al.
Publicado: (2012)

CD80 Costimulation Is Essential for the Induction of Airway Eosinophilia
por: Harris, Nicola, et al.
Publicado: (1997)

Tipping the Balance in Metabolic Regulation: Regulating Regulatory T Cells by Costimulation
por: Qi, Ling
Publicado: (2014)

Mir-29b mediates the regulation of Nrf2 on airway epithelial remodeling and Th1/Th2 differentiation in COPD rats
por: Chi, Yumin, et al.
Publicado: (2019)

IL-23 signaling enhances Th2 polarization and regulates allergic airway inflammation
por: Peng, Juan, et al.
Publicado: (2009)

Engineering the next generation of cell-based therapeutics
por: Bashor, Caleb J., et al.
Publicado: (2022)

Inhibitors of mitogen-activated protein kinases differentially regulate costimulated T cell cytokine production and mouse airway eosinophilia
por: Chialda, Ligia, et al.
Publicado: (2005)

Aryl Hydrocarbon Receptor Activation Ameliorates Acute Respiratory Distress Syndrome through Regulation of Th17 and Th22 Cells in the Lungs
por: Holloman, Bryan Latrell, et al.
Publicado: (2023)

New aspects the regulation of immune response through balance Th1/Th2 cytokines
por: Tymoshok, Natalia O, et al.
Publicado: (2014)

IL-4 enhances IL-10 production in Th1 cells: implications for Th1 and Th2 regulation
por: Mitchell, Ruth E., et al.
Publicado: (2017)

Transcriptional regulation of Th2 differentiation
por: Paul, William E, et al.
Publicado: (2006)

Th1/Th2 cross-regulation and the discovery of IL-10
por: Bashyam, Hema
Publicado: (2007)

Lymphotoxin Is Required for Maintaining Physiological Levels of Serum IgE That Minimizes Th1-mediated Airway Inflammation
por: Kang, Hyung-Sik, et al.
Publicado: (2003)

Ovarian Extirpations. The 109th and 110th Cases, and 75th and 76th Successful Operations
por: Clay, Charles
Publicado: (1864)

Anti-Chlamydial Th17 Responses Are Controlled by the Inducible Costimulator Partially through Phosphoinositide 3-Kinase Signaling
por: Gao, Xiaoling, et al.
Publicado: (2012)

Sex-Based Selectivity of PPARγ Regulation in Th1, Th2, and Th17 Differentiation
por: Park, Hong-Jai, et al.
Publicado: (2016)

Pathogenic Th2 (Tpath2) cells in airway inflammation
por: Endo, Yusuke, et al.
Publicado: (2015)

Itk Negatively Regulates Induction of T Cell Proliferation by CD28 Costimulation
por: Liao, X. Charlene, et al.
Publicado: (1997)

CD28 Costimulation Regulates Genome-Wide Effects on Alternative Splicing
por: Butte, Manish J., et al.
Publicado: (2012)

Keratinocytes costimulate naive human T cells via CD2: a potential target to prevent the development of proinflammatory Th1 cells in the skin
por: Orlik, Christian, et al.
Publicado: (2019)

Lipopolysaccharide Exposure Alleviates Asthma in Mice by Regulating Th1/Th2 and Treg/Th17 Balance
por: Ding, Fengxia, et al.
Publicado: (2018)

Th1/Th2 Differentiation and B Cell Function by the Atypical PKCs and Their Regulators
por: Martin, Pilar, et al.
Publicado: (2012)

Th1 and Th2 cytokines regulate proteoglycan-specific autoantibody isotypes and arthritis
por: Kaplan, Charles, et al.
Publicado: (2002)

Saikosaponin A Inhibits Breast Cancer by Regulating Th1/Th2 Balance
por: Zhao, Xin, et al.
Publicado: (2019)

Bifidobacterium infantis Relieves Allergic Asthma in Mice by Regulating Th1/Th2
por: Wang, Wenlan, et al.
Publicado: (2020)

Bach2: A Key Regulator in Th2-Related Immune Cells and Th2 Immune Response
por: Liu, Guo, et al.
Publicado: (2022)

New battlefields for costimulation
por: Martin-Orozco, Natalia, et al.
Publicado: (2006)

Non-apoptotic Fas (CD95) Signaling on T Cells Regulates the Resolution of Th2-Mediated Inflammation
por: Williams, Jesse W., et al.
Publicado: (2018)

CD43 interaction with ezrin-radixin-moesin (ERM) proteins regulates T-cell trafficking and CD43 phosphorylation
por: Cannon, J. L., et al.
Publicado: (2011)

A Proteomic View at T Cell Costimulation
por: Lichtenfels, Rudolf, et al.
Publicado: (2012)

A qPCR-based metric of Th2 airway inflammation in asthma
por: Bhakta, Nirav R, et al.
Publicado: (2013)

Cytokine Regulation of Lung Th17 Response to Airway Immunization using LPS Adjuvant
por: Caucheteux, Stephan M., et al.
Publicado: (2016)

Th1/Th2 cytokines profile in overweight/obese young adults and their correlation with airways inflammation
por: Salem, Ayad M.
Publicado: (2021)

Ndrg1 is a T-cell clonal anergy factor negatively regulated by CD28 costimulation and interleukin-2
por: Oh, Yu Mi, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_d01dov7lfsg56ntjc2dbi37aqm