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Closed-channel block of BK potassium channels by bbTBA requires partial activation

Blockade of large-conductance Ca(2+)-activated K(+) (BK) channels by the bulky quaternary ammonium compound, N-(4-[benzoyl]benzyl)-N,N,N-tributylammonium (bbTBA), exhibits features consistent with blockade of both closed and open states. Here, we examine block of closed BK channels by bbTBA and how...

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Detalles Bibliográficos
Autores principales:	Tang, Qiong-Yao, Zeng, Xu-Hui, Lingle, Christopher J.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768800/ https://www.ncbi.nlm.nih.gov/pubmed/19858359 http://dx.doi.org/10.1085/jgp.200910251

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