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It takes two to tango to the melanosome

The role of clathrin adaptor proteins in sorting cargo in the biosynthetic and recycling routes is an area of intense research. In this issue, Delevoye et al. (2009. J. Cell Biol. doi:10.1083/jcb.200907122) show that a close interaction between the clathrin adaptor AP-1 and a kinesin motor KIF13A is...

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Detalles Bibliográficos
Autores principales: Lakkaraju, Aparna, Carvajal-Gonzalez, Jose Maria, Rodriguez-Boulan, Enrique
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768836/
https://www.ncbi.nlm.nih.gov/pubmed/19841135
http://dx.doi.org/10.1083/jcb.200909100
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author Lakkaraju, Aparna
Carvajal-Gonzalez, Jose Maria
Rodriguez-Boulan, Enrique
author_facet Lakkaraju, Aparna
Carvajal-Gonzalez, Jose Maria
Rodriguez-Boulan, Enrique
author_sort Lakkaraju, Aparna
collection PubMed
description The role of clathrin adaptor proteins in sorting cargo in the biosynthetic and recycling routes is an area of intense research. In this issue, Delevoye et al. (2009. J. Cell Biol. doi:10.1083/jcb.200907122) show that a close interaction between the clathrin adaptor AP-1 and a kinesin motor KIF13A is essential for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes and for organelle biogenesis.
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spelling pubmed-27688362010-04-19 It takes two to tango to the melanosome Lakkaraju, Aparna Carvajal-Gonzalez, Jose Maria Rodriguez-Boulan, Enrique J Cell Biol Reviews The role of clathrin adaptor proteins in sorting cargo in the biosynthetic and recycling routes is an area of intense research. In this issue, Delevoye et al. (2009. J. Cell Biol. doi:10.1083/jcb.200907122) show that a close interaction between the clathrin adaptor AP-1 and a kinesin motor KIF13A is essential for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes and for organelle biogenesis. The Rockefeller University Press 2009-10-19 /pmc/articles/PMC2768836/ /pubmed/19841135 http://dx.doi.org/10.1083/jcb.200909100 Text en © 2009 Lakkaraju et al. This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jcb.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Reviews
Lakkaraju, Aparna
Carvajal-Gonzalez, Jose Maria
Rodriguez-Boulan, Enrique
It takes two to tango to the melanosome
title It takes two to tango to the melanosome
title_full It takes two to tango to the melanosome
title_fullStr It takes two to tango to the melanosome
title_full_unstemmed It takes two to tango to the melanosome
title_short It takes two to tango to the melanosome
title_sort it takes two to tango to the melanosome
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768836/
https://www.ncbi.nlm.nih.gov/pubmed/19841135
http://dx.doi.org/10.1083/jcb.200909100
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