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It takes two to tango to the melanosome
The role of clathrin adaptor proteins in sorting cargo in the biosynthetic and recycling routes is an area of intense research. In this issue, Delevoye et al. (2009. J. Cell Biol. doi:10.1083/jcb.200907122) show that a close interaction between the clathrin adaptor AP-1 and a kinesin motor KIF13A is...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768836/ https://www.ncbi.nlm.nih.gov/pubmed/19841135 http://dx.doi.org/10.1083/jcb.200909100 |
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author | Lakkaraju, Aparna Carvajal-Gonzalez, Jose Maria Rodriguez-Boulan, Enrique |
author_facet | Lakkaraju, Aparna Carvajal-Gonzalez, Jose Maria Rodriguez-Boulan, Enrique |
author_sort | Lakkaraju, Aparna |
collection | PubMed |
description | The role of clathrin adaptor proteins in sorting cargo in the biosynthetic and recycling routes is an area of intense research. In this issue, Delevoye et al. (2009. J. Cell Biol. doi:10.1083/jcb.200907122) show that a close interaction between the clathrin adaptor AP-1 and a kinesin motor KIF13A is essential for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes and for organelle biogenesis. |
format | Text |
id | pubmed-2768836 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-27688362010-04-19 It takes two to tango to the melanosome Lakkaraju, Aparna Carvajal-Gonzalez, Jose Maria Rodriguez-Boulan, Enrique J Cell Biol Reviews The role of clathrin adaptor proteins in sorting cargo in the biosynthetic and recycling routes is an area of intense research. In this issue, Delevoye et al. (2009. J. Cell Biol. doi:10.1083/jcb.200907122) show that a close interaction between the clathrin adaptor AP-1 and a kinesin motor KIF13A is essential for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes and for organelle biogenesis. The Rockefeller University Press 2009-10-19 /pmc/articles/PMC2768836/ /pubmed/19841135 http://dx.doi.org/10.1083/jcb.200909100 Text en © 2009 Lakkaraju et al. This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jcb.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/). |
spellingShingle | Reviews Lakkaraju, Aparna Carvajal-Gonzalez, Jose Maria Rodriguez-Boulan, Enrique It takes two to tango to the melanosome |
title | It takes two to tango to the melanosome |
title_full | It takes two to tango to the melanosome |
title_fullStr | It takes two to tango to the melanosome |
title_full_unstemmed | It takes two to tango to the melanosome |
title_short | It takes two to tango to the melanosome |
title_sort | it takes two to tango to the melanosome |
topic | Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768836/ https://www.ncbi.nlm.nih.gov/pubmed/19841135 http://dx.doi.org/10.1083/jcb.200909100 |
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