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T-bet–dependent S1P(5) expression in NK cells promotes egress from lymph nodes and bone marrow

During a screen for ethylnitrosourea-induced mutations in mice affecting blood natural killer (NK) cells, we identified a strain, designated Duane, in which NK cells were reduced in blood and spleen but increased in lymph nodes (LNs) and bone marrow (BM). The accumulation of NK cells in LNs reflecte...

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Detalles Bibliográficos
Autores principales: Jenne, Craig N., Enders, Anselm, Rivera, Richard, Watson, Susan R., Bankovich, Alexander J., Pereira, Joao P., Xu, Ying, Roots, Carla M., Beilke, Joshua N., Banerjee, Arnob, Reiner, Steven L., Miller, Sara A., Weinmann, Amy S., Goodnow, Chris C., Lanier, Lewis L., Cyster, Jason G., Chun, Jerold
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768857/
https://www.ncbi.nlm.nih.gov/pubmed/19808259
http://dx.doi.org/10.1084/jem.20090525