KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A(*)11 while diminishing avidity for HLA-C

Human killer cell immunoglobulin-like receptors (KIRs) are distinguished by expansion of activating KIR2DS, whose ligands and functions remain poorly understood. The oldest, most prevalent KIR2DS is KIR2DS4, which is represented by a variable balance between “full-length” and “deleted” forms. We fin...

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Detalles Bibliográficos
Autores principales: Graef, Thorsten, Moesta, Achim K., Norman, Paul J., Abi-Rached, Laurent, Vago, Luca, Older Aguilar, Anastazia M., Gleimer, Michael, Hammond, John A., Guethlein, Lisbeth A., Bushnell, David A., Robinson, Philip J., Parham, Peter
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768862/
https://www.ncbi.nlm.nih.gov/pubmed/19858347
http://dx.doi.org/10.1084/jem.20091010

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