Common variants in polygenic schizophrenia

Common variant single-nucleotide polymorphisms at the MHC locus have recently been associated with schizophrenia. Together with known associations with rare copy-number variants affecting many genes, this reveals the highly polygenic etiology of the disease.

Detalles Bibliográficos
Autores principales: Glessner, Joseph T, Hakonarson, Hakon
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768969/
https://www.ncbi.nlm.nih.gov/pubmed/19785721
http://dx.doi.org/10.1186/gb-2009-10-9-236
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author Glessner, Joseph T
Hakonarson, Hakon
author_facet Glessner, Joseph T
Hakonarson, Hakon
author_sort Glessner, Joseph T
collection PubMed
description Common variant single-nucleotide polymorphisms at the MHC locus have recently been associated with schizophrenia. Together with known associations with rare copy-number variants affecting many genes, this reveals the highly polygenic etiology of the disease.
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spelling pubmed-27689692010-09-29 Common variants in polygenic schizophrenia Glessner, Joseph T Hakonarson, Hakon Genome Biol Minireview Common variant single-nucleotide polymorphisms at the MHC locus have recently been associated with schizophrenia. Together with known associations with rare copy-number variants affecting many genes, this reveals the highly polygenic etiology of the disease. BioMed Central 2009 2009-09-29 /pmc/articles/PMC2768969/ /pubmed/19785721 http://dx.doi.org/10.1186/gb-2009-10-9-236 Text en Copyright © 2009 BioMed Central Ltd
spellingShingle Minireview
Glessner, Joseph T
Hakonarson, Hakon
Common variants in polygenic schizophrenia
title Common variants in polygenic schizophrenia
title_full Common variants in polygenic schizophrenia
title_fullStr Common variants in polygenic schizophrenia
title_full_unstemmed Common variants in polygenic schizophrenia
title_short Common variants in polygenic schizophrenia
title_sort common variants in polygenic schizophrenia
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768969/
https://www.ncbi.nlm.nih.gov/pubmed/19785721
http://dx.doi.org/10.1186/gb-2009-10-9-236
work_keys_str_mv AT glessnerjosepht commonvariantsinpolygenicschizophrenia
AT hakonarsonhakon commonvariantsinpolygenicschizophrenia

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