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Dioxin-Dependent and Dioxin-Independent Gene Batteries: Comparison of Liver and Kidney in AHR-Null Mice

The aryl hydrocarbon receptor (AHR) is a widely expressed ligand-dependent transcription factor that mediates cellular responses to dioxins and other planar aromatic hydrocarbons. Ahr-null mice are refractory to the toxic effects of dioxin exposure. Although some mechanistic aspects of AHR activity...

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Detalles Bibliográficos
Autores principales:	Boutros, Paul C., Bielefeld, Kirsten A., Pohjanvirta, Raimo, Harper, Patricia A.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	Systems Toxicology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769058/ https://www.ncbi.nlm.nih.gov/pubmed/19759094 http://dx.doi.org/10.1093/toxsci/kfp191

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