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Improving effector functions of antibodies for cancer treatment: Enhancing ADCC and CDC

As platforms for therapeutic agents, monoclonal antibodies (MAbs) have already been approved, and several MAbs have demonstrated clinical effectiveness in a variety of malignancies. However, several issues have also been emerging in antibody therapy, such as high cost and insufficient drug action. R...

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Detalles Bibliográficos
Autores principales: Natsume, Akito, Niwa, Rinpei, Satoh, Mitsuo
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769226/
https://www.ncbi.nlm.nih.gov/pubmed/19920917