Apoptotic and chemotherapeutic properties of iron (III)-salophene in an ovarian cancer animal model

The cytotoxicity of organometallic compounds iron(III)-, cobalt(III)-, manganese(II)-, and copper(II)-salophene (-SP) on platinum-resistant ovarian cancer cell lines was compared. Fe-SP displayed selective cytotoxicity (IC(50) at ~1 μM) against SKOV-3 and OVCAR-3 cell lines while Co-SP caused cytoto...

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Detalles Bibliográficos
Autores principales: Lange, Thilo S, McCourt, Carolyn, Singh, Rakesh K, Kim, Kyu Kwang, Singh, Ajay P, Luisi, Brian S, Alptürk, Onur, Strongin, Robert M, Brard, Laurent
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2009
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769229/
https://www.ncbi.nlm.nih.gov/pubmed/19920918

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