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Pulmonary metastases from primary hepatocellular carcinoma in a 26-year-old patient: a case report

Hepatocellular carcinoma is a primary tumor of the liver, which usually develops in the setting of chronic liver disease, particularly viral hepatitis. The diagnosis of hepatocellular carcinoma can be difficult, and often requires the use of serum markers, one or more imaging modalities, and histolo...

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Detalles Bibliográficos
Autores principales: Assed, Carla, Marchiori, Edson, Zanetti, Gláucia, Mano, Claudia Mauro, Sarcinelli-Luz, Branca, Vianna, Flávia Gavinho, Carvalho, Juliana França, Santos, Isabella Guedes, Santos, Alair Augusto, Vianna, Alberto Domingues
Formato: Texto
Lenguaje:English
Publicado: Cases Network Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769276/
https://www.ncbi.nlm.nih.gov/pubmed/19918566
http://dx.doi.org/10.4076/1757-1626-2-6256
Descripción
Sumario:Hepatocellular carcinoma is a primary tumor of the liver, which usually develops in the setting of chronic liver disease, particularly viral hepatitis. The diagnosis of hepatocellular carcinoma can be difficult, and often requires the use of serum markers, one or more imaging modalities, and histological confirmation. The authors describe a case of a 26-year-old woman with hepatocellular carcinoma and multiple pulmonary metastases. She presented with hepatomegaly and sporadic fever, and had negative hepatitis serology, normal alkaline phosphatase, and a rising serum alpha-fetoprotein level. The diagnosis was confirmed by histopathology, after percutaneous liver biopsy. Although the patient was in good health condition and had few symptoms, there was no possibility of treatment due to the extension of the liver tumor and the number of pulmonary metastases.