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Genetic effect of CysLTR2 polymorphisms on its mRNA synthesis and stabilization

BACKGROUND: We previously demonstrated that single nucleotide polymorphism (SNP) and haplotypes were associated with aspirin hypersensitivity in asthmatics. We investigated the genetic effects of the SNPs and haplotypes on the expression of the CysLTR2 gene. METHODS: We measured CysLTR2 protein and...

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Detalles Bibliográficos
Autores principales: Shin, Jeong-Ah, Chang, Hun Soo, Park, Se-Min, Jang, An-Soo, Park, Sung Woo, Park, Jong Sook, Uh, Soo-Taek, Il Lim, Gune, Rhim, Taiyoun, Kim, Mi-Kyeong, Choi, Inseon S, Chung, Il Yup, Park, Byung Lae, Shin, Hyoung Doo, Park, Choon-Sik
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770054/
https://www.ncbi.nlm.nih.gov/pubmed/19840403
http://dx.doi.org/10.1186/1471-2350-10-106