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HIV reverse transcriptase: Structural interpretation of drug resistant genetic variants from India

The reverse transcriptase (RT) enzyme is the prime target of nucleoside/ nucleotide (NRTI) and non-nucleoside (NNRTI) reverse transcriptase inhibitors. Here we investigate the structural basis of effects of drug-resistance mutations in clade C RT using three-dimensional structural modeling. Apropos...

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Detalles Bibliográficos
Autores principales:	Kandathil, Abraham Joseph, Joseph, Agnel Praveen, Kannangai, Rajesh, Srinivasan, Narayanaswamy, Abraham, Oriapadickal Cherian, Pulimood, Susanne Alexander, Sridharan, Gopalan
Formato:	Texto
Lenguaje:	English
Publicado:	Biomedical Informatics 2009
Materias:	Hypothesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770369/ https://www.ncbi.nlm.nih.gov/pubmed/20011151

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