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Safety, efficacy and patient acceptability of the combined estrogen and progestin transdermal contraceptive patch: a review

The worldwide introduction of the first, unique patch for hormonal contraception (ethinyl estradiol/norelgestromin, EE/NGMN patch) was widely recognized as a significant event in the development of drug delivery systems. This innovation offers a number of advantages over the oral route, and extensiv...

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Detalles Bibliográficos
Autor principal: Graziottin, Alessandra
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770395/
https://www.ncbi.nlm.nih.gov/pubmed/19920983
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author Graziottin, Alessandra
author_facet Graziottin, Alessandra
author_sort Graziottin, Alessandra
collection PubMed
description The worldwide introduction of the first, unique patch for hormonal contraception (ethinyl estradiol/norelgestromin, EE/NGMN patch) was widely recognized as a significant event in the development of drug delivery systems. This innovation offers a number of advantages over the oral route, and extensive clinical trials have proved its safety, efficacy, effectiveness, and tolerability. The weekly administration and ease of use/simplicity of the EE/NGMN patch contribute to its acceptability, and help to resolve the two main problems of non-adherence, namely early discontinuation and inconsistent use. The patch offers additional benefits to adolescents (improvement of dysmenorrhea and acne), adults (improvement in emotional and physical well-being, premenstrual syndrome, and menstrual irregularities), and perimenopausal women (correction of hormonal imbalance, modulation of premenopausal symptoms), thus providing high satisfaction rates (in nearly 90% of users). Since its introduction, the transdermal contraceptive patch has proved to be a useful choice for women who seek a convenient formulation which is easy to use, with additional, non-contraceptive tailored benefits for all the ages.
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spelling pubmed-27703952009-11-17 Safety, efficacy and patient acceptability of the combined estrogen and progestin transdermal contraceptive patch: a review Graziottin, Alessandra Patient Prefer Adherence Review The worldwide introduction of the first, unique patch for hormonal contraception (ethinyl estradiol/norelgestromin, EE/NGMN patch) was widely recognized as a significant event in the development of drug delivery systems. This innovation offers a number of advantages over the oral route, and extensive clinical trials have proved its safety, efficacy, effectiveness, and tolerability. The weekly administration and ease of use/simplicity of the EE/NGMN patch contribute to its acceptability, and help to resolve the two main problems of non-adherence, namely early discontinuation and inconsistent use. The patch offers additional benefits to adolescents (improvement of dysmenorrhea and acne), adults (improvement in emotional and physical well-being, premenstrual syndrome, and menstrual irregularities), and perimenopausal women (correction of hormonal imbalance, modulation of premenopausal symptoms), thus providing high satisfaction rates (in nearly 90% of users). Since its introduction, the transdermal contraceptive patch has proved to be a useful choice for women who seek a convenient formulation which is easy to use, with additional, non-contraceptive tailored benefits for all the ages. Dove Medical Press 2008-02-02 /pmc/articles/PMC2770395/ /pubmed/19920983 Text en © 2008 Dove Medical Press Limited. All rights reserved
spellingShingle Review
Graziottin, Alessandra
Safety, efficacy and patient acceptability of the combined estrogen and progestin transdermal contraceptive patch: a review
title Safety, efficacy and patient acceptability of the combined estrogen and progestin transdermal contraceptive patch: a review
title_full Safety, efficacy and patient acceptability of the combined estrogen and progestin transdermal contraceptive patch: a review
title_fullStr Safety, efficacy and patient acceptability of the combined estrogen and progestin transdermal contraceptive patch: a review
title_full_unstemmed Safety, efficacy and patient acceptability of the combined estrogen and progestin transdermal contraceptive patch: a review
title_short Safety, efficacy and patient acceptability of the combined estrogen and progestin transdermal contraceptive patch: a review
title_sort safety, efficacy and patient acceptability of the combined estrogen and progestin transdermal contraceptive patch: a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770395/
https://www.ncbi.nlm.nih.gov/pubmed/19920983
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