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HIV-1 neutralization by monoclonal antibody against conserved region 2 and patterns of epitope exposure on the surface of native viruses

BACKGROUND: Conserved neutralizing epitopes are considered to be a key role for eliciting broadly neutralizing antibody (NAb). Previously, two conserved neutralizing epitopes of HIV-1 CRF01_AE envelope were identified at amino acid 93-112 of the C1 (C1E) and at 218-239 of the C2 (C2E) regions. To ac...

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Detalles Bibliográficos
Autores principales:	Sreepian, Apichai, Permmongkol, Jongruk, Kantakamalakul, Wannee, Siritantikorn, Sontana, Tanlieng, Nattaya, Sutthent, Ruengpung
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770445/ https://www.ncbi.nlm.nih.gov/pubmed/19821992 http://dx.doi.org/10.1186/1476-8518-7-5

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