Phylogenetic analysis and characterization of Korean orf virus from dairy goats: case report

An outbreak of orf virus infection in dairy goats in Korea was investigated. Suspected samples of the skin and lip of affected goats were sent to the laboratory for more exact diagnosis. Orf virus was detected by electron microscopy and viral DNA was identified by PCR. To reveal the genetic characte...

Descripción completa

Detalles Bibliográficos
Autores principales: Oem, Jae-Ku, Roh, In-Soon, Lee, Kyung-Hyun, Lee, Kyoung-Ki, Kim, Hye-Ryoung, Jean, Young-Hwa, Lee, O-Soo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770494/
https://www.ncbi.nlm.nih.gov/pubmed/19835585
http://dx.doi.org/10.1186/1743-422X-6-167
_version_ 1782173669072568320
author Oem, Jae-Ku
Roh, In-Soon
Lee, Kyung-Hyun
Lee, Kyoung-Ki
Kim, Hye-Ryoung
Jean, Young-Hwa
Lee, O-Soo
author_facet Oem, Jae-Ku
Roh, In-Soon
Lee, Kyung-Hyun
Lee, Kyoung-Ki
Kim, Hye-Ryoung
Jean, Young-Hwa
Lee, O-Soo
author_sort Oem, Jae-Ku
collection PubMed
description An outbreak of orf virus infection in dairy goats in Korea was investigated. Suspected samples of the skin and lip of affected goats were sent to the laboratory for more exact diagnosis. Orf virus was detected by electron microscopy and viral DNA was identified by PCR. To reveal the genetic characteristics of the Korean strain (ORF/09/Korea), the sequences of the major envelope protein (B2L) and orf virus interferon resistance (VIR) genes were determined and then compared with published reference sequences. Phylogenetic analysis revealed that the ORF/09/Korea strain was closest to the isolates (Taiping) from Taiwan. This is believed to be the first report on the molecular characterization of orf virus in Korea.
format Text
id pubmed-2770494
institution National Center for Biotechnology Information
language English
publishDate 2009
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-27704942009-10-30 Phylogenetic analysis and characterization of Korean orf virus from dairy goats: case report Oem, Jae-Ku Roh, In-Soon Lee, Kyung-Hyun Lee, Kyoung-Ki Kim, Hye-Ryoung Jean, Young-Hwa Lee, O-Soo Virol J Case Report An outbreak of orf virus infection in dairy goats in Korea was investigated. Suspected samples of the skin and lip of affected goats were sent to the laboratory for more exact diagnosis. Orf virus was detected by electron microscopy and viral DNA was identified by PCR. To reveal the genetic characteristics of the Korean strain (ORF/09/Korea), the sequences of the major envelope protein (B2L) and orf virus interferon resistance (VIR) genes were determined and then compared with published reference sequences. Phylogenetic analysis revealed that the ORF/09/Korea strain was closest to the isolates (Taiping) from Taiwan. This is believed to be the first report on the molecular characterization of orf virus in Korea. BioMed Central 2009-10-16 /pmc/articles/PMC2770494/ /pubmed/19835585 http://dx.doi.org/10.1186/1743-422X-6-167 Text en Copyright © 2009 Oem et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Oem, Jae-Ku
Roh, In-Soon
Lee, Kyung-Hyun
Lee, Kyoung-Ki
Kim, Hye-Ryoung
Jean, Young-Hwa
Lee, O-Soo
Phylogenetic analysis and characterization of Korean orf virus from dairy goats: case report
title Phylogenetic analysis and characterization of Korean orf virus from dairy goats: case report
title_full Phylogenetic analysis and characterization of Korean orf virus from dairy goats: case report
title_fullStr Phylogenetic analysis and characterization of Korean orf virus from dairy goats: case report
title_full_unstemmed Phylogenetic analysis and characterization of Korean orf virus from dairy goats: case report
title_short Phylogenetic analysis and characterization of Korean orf virus from dairy goats: case report
title_sort phylogenetic analysis and characterization of korean orf virus from dairy goats: case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770494/
https://www.ncbi.nlm.nih.gov/pubmed/19835585
http://dx.doi.org/10.1186/1743-422X-6-167
work_keys_str_mv AT oemjaeku phylogeneticanalysisandcharacterizationofkoreanorfvirusfromdairygoatscasereport
AT rohinsoon phylogeneticanalysisandcharacterizationofkoreanorfvirusfromdairygoatscasereport
AT leekyunghyun phylogeneticanalysisandcharacterizationofkoreanorfvirusfromdairygoatscasereport
AT leekyoungki phylogeneticanalysisandcharacterizationofkoreanorfvirusfromdairygoatscasereport
AT kimhyeryoung phylogeneticanalysisandcharacterizationofkoreanorfvirusfromdairygoatscasereport
AT jeanyounghwa phylogeneticanalysisandcharacterizationofkoreanorfvirusfromdairygoatscasereport
AT leeosoo phylogeneticanalysisandcharacterizationofkoreanorfvirusfromdairygoatscasereport

Ejemplares similares