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CpG-depleted promoters harbor tissue-specific transcription factor binding signals—implications for motif overrepresentation analyses
Motif overrepresentation analysis of proximal promoters is a common approach to characterize the regulatory properties of co-expressed sets of genes. Here we show that these approaches perform well on mammalian CpG-depleted promoter sets that regulate expression in terminally differentiated tissues...
Autores principales: | Roider, Helge G., Lenhard, Boris, Kanhere, Aditi, Haas, Stefan A., Vingron, Martin |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770660/ https://www.ncbi.nlm.nih.gov/pubmed/19736212 http://dx.doi.org/10.1093/nar/gkp682 |
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