Structural mechanisms for the 5′-CCWGG sequence recognition by the N- and C-terminal domains of EcoRII

EcoRII restriction endonuclease is specific for the 5′-CCWGG sequence (W stands for A or T); however, it shows no activity on a single recognition site. To activate cleavage it requires binding of an additional target site as an allosteric effector. EcoRII dimer consists of three structural units: a...

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Detalles Bibliográficos
Autores principales: Golovenko, Dmitrij, Manakova, Elena, Tamulaitiene, Giedre, Grazulis, Saulius, Siksnys, Virginijus
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770665/
https://www.ncbi.nlm.nih.gov/pubmed/19729506
http://dx.doi.org/10.1093/nar/gkp699

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770665/
https://www.ncbi.nlm.nih.gov/pubmed/19729506
http://dx.doi.org/10.1093/nar/gkp699

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