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Structural mechanisms for the 5′-CCWGG sequence recognition by the N- and C-terminal domains of EcoRII
EcoRII restriction endonuclease is specific for the 5′-CCWGG sequence (W stands for A or T); however, it shows no activity on a single recognition site. To activate cleavage it requires binding of an additional target site as an allosteric effector. EcoRII dimer consists of three structural units: a...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770665/ https://www.ncbi.nlm.nih.gov/pubmed/19729506 http://dx.doi.org/10.1093/nar/gkp699 |