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Biochemical properties and base excision repair complex formation of apurinic/apyrimidinic endonuclease from Pyrococcus furiosus
Apurinic/apyrimidinic (AP) sites are the most frequently found mutagenic lesions in DNA, and they arise mainly from spontaneous base loss or modified base removal by damage-specific DNA glycosylases. AP sites are cleaved by AP endonucleases, and the resultant gaps in the DNA are repaired by DNA poly...
Autores principales: | Kiyonari, Shinichi, Tahara, Saki, Shirai, Tsuyoshi, Iwai, Shigenori, Ishino, Sonoko, Ishino, Yoshizumi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770678/ https://www.ncbi.nlm.nih.gov/pubmed/19734344 http://dx.doi.org/10.1093/nar/gkp720 |
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