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Interferons and their potential in the treatment of ocular inflammation
Since their discovery in the 1950s interferons have been the scope of investigation in many diseases as therapeutic as well as pathogenetic factors. We know they have immune stimulatory and immune regulatory effects. This apparently counter-intuitive mechanism can be summarized as immunomodulatory a...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Dove Medical Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770867/ https://www.ncbi.nlm.nih.gov/pubmed/19898628 |
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author | Mackensen, Friederike Max, Regina Becker, Matthias D |
author_facet | Mackensen, Friederike Max, Regina Becker, Matthias D |
author_sort | Mackensen, Friederike |
collection | PubMed |
description | Since their discovery in the 1950s interferons have been the scope of investigation in many diseases as therapeutic as well as pathogenetic factors. We know they have immune stimulatory and immune regulatory effects. This apparently counter-intuitive mechanism can be summarized as immunomodulatory action and seems to be very effective in a number of ocular inflammatory diseases. We review the current knowledge of interferons in immunity and autoimmunity and show their use in clinical ophthalmologic practice. |
format | Text |
id | pubmed-2770867 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-27708672009-11-06 Interferons and their potential in the treatment of ocular inflammation Mackensen, Friederike Max, Regina Becker, Matthias D Clin Ophthalmol Review Since their discovery in the 1950s interferons have been the scope of investigation in many diseases as therapeutic as well as pathogenetic factors. We know they have immune stimulatory and immune regulatory effects. This apparently counter-intuitive mechanism can be summarized as immunomodulatory action and seems to be very effective in a number of ocular inflammatory diseases. We review the current knowledge of interferons in immunity and autoimmunity and show their use in clinical ophthalmologic practice. Dove Medical Press 2009 2009-10-19 /pmc/articles/PMC2770867/ /pubmed/19898628 Text en © 2009 Mackensen et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited. |
spellingShingle | Review Mackensen, Friederike Max, Regina Becker, Matthias D Interferons and their potential in the treatment of ocular inflammation |
title | Interferons and their potential in the treatment of ocular inflammation |
title_full | Interferons and their potential in the treatment of ocular inflammation |
title_fullStr | Interferons and their potential in the treatment of ocular inflammation |
title_full_unstemmed | Interferons and their potential in the treatment of ocular inflammation |
title_short | Interferons and their potential in the treatment of ocular inflammation |
title_sort | interferons and their potential in the treatment of ocular inflammation |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770867/ https://www.ncbi.nlm.nih.gov/pubmed/19898628 |
work_keys_str_mv | AT mackensenfriederike interferonsandtheirpotentialinthetreatmentofocularinflammation AT maxregina interferonsandtheirpotentialinthetreatmentofocularinflammation AT beckermatthiasd interferonsandtheirpotentialinthetreatmentofocularinflammation |