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Interferons and their potential in the treatment of ocular inflammation

Since their discovery in the 1950s interferons have been the scope of investigation in many diseases as therapeutic as well as pathogenetic factors. We know they have immune stimulatory and immune regulatory effects. This apparently counter-intuitive mechanism can be summarized as immunomodulatory a...

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Detalles Bibliográficos
Autores principales: Mackensen, Friederike, Max, Regina, Becker, Matthias D
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770867/
https://www.ncbi.nlm.nih.gov/pubmed/19898628
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author Mackensen, Friederike
Max, Regina
Becker, Matthias D
author_facet Mackensen, Friederike
Max, Regina
Becker, Matthias D
author_sort Mackensen, Friederike
collection PubMed
description Since their discovery in the 1950s interferons have been the scope of investigation in many diseases as therapeutic as well as pathogenetic factors. We know they have immune stimulatory and immune regulatory effects. This apparently counter-intuitive mechanism can be summarized as immunomodulatory action and seems to be very effective in a number of ocular inflammatory diseases. We review the current knowledge of interferons in immunity and autoimmunity and show their use in clinical ophthalmologic practice.
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spelling pubmed-27708672009-11-06 Interferons and their potential in the treatment of ocular inflammation Mackensen, Friederike Max, Regina Becker, Matthias D Clin Ophthalmol Review Since their discovery in the 1950s interferons have been the scope of investigation in many diseases as therapeutic as well as pathogenetic factors. We know they have immune stimulatory and immune regulatory effects. This apparently counter-intuitive mechanism can be summarized as immunomodulatory action and seems to be very effective in a number of ocular inflammatory diseases. We review the current knowledge of interferons in immunity and autoimmunity and show their use in clinical ophthalmologic practice. Dove Medical Press 2009 2009-10-19 /pmc/articles/PMC2770867/ /pubmed/19898628 Text en © 2009 Mackensen et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Review
Mackensen, Friederike
Max, Regina
Becker, Matthias D
Interferons and their potential in the treatment of ocular inflammation
title Interferons and their potential in the treatment of ocular inflammation
title_full Interferons and their potential in the treatment of ocular inflammation
title_fullStr Interferons and their potential in the treatment of ocular inflammation
title_full_unstemmed Interferons and their potential in the treatment of ocular inflammation
title_short Interferons and their potential in the treatment of ocular inflammation
title_sort interferons and their potential in the treatment of ocular inflammation
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770867/
https://www.ncbi.nlm.nih.gov/pubmed/19898628
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