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Drosophila KDM2 is a H3K4me3 demethylase regulating nucleolar organization

BACKGROUND: CG11033 (dKDM2) is the Drosophila homolog of the gene KDM2B. dKDM2 has been known to possess histone lysine demethylase activity towards H3K36me2 in cell lines and it regulates H2A ubiquitination. The human homolog of the gene has dual activity towards H3K36me2 as well as H3K4me3, and pl...

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Detalles Bibliográficos
Autores principales: Kavi, Harsh H, Birchler, James A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771041/
https://www.ncbi.nlm.nih.gov/pubmed/19852816
http://dx.doi.org/10.1186/1756-0500-2-217

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