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Characterisation of influenza A viruses with mutations in segment 5 packaging signals

Influenza A virus vRNA segments contain specific packaging signals at their termini that overlap the coding regions. To further characterise segment 5 packaging signals, we introduced synonymous mutations into the terminal coding regions of the vRNA and characterised the replicative fitness of the r...

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Detalles Bibliográficos
Autores principales: Hutchinson, Edward C., Wise, Helen M., Kudryavtseva, Katerine, Curran, Martin D., Digard, Paul
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771075/
https://www.ncbi.nlm.nih.gov/pubmed/19840659
http://dx.doi.org/10.1016/j.vaccine.2009.05.053