Intracameral Recombinant Tissue Plasminogen Activator for Refractory Glaucoma Secondary to a Fungal Corneal Abscess

We present a 78-year-old patient who developed refractory glaucoma following a fungal infection of the corneal incision after cataract extraction with posterior chamber intraocular lens implantation. An anterior chamber injection of 0.1 ml recombinant tissue plasminogen activator (25 mcg/0.1 mL) was...

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Detalles Bibliográficos
Autores principales: Katz, L. Jay, Stirbu, Oana, Willis, Garth, Ichhpujani, Parul
Formato: Texto
Lenguaje:English
Publicado: Bentham Open 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771269/
https://www.ncbi.nlm.nih.gov/pubmed/19888435
http://dx.doi.org/10.2174/1874364100903010075
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author Katz, L. Jay
Stirbu, Oana
Willis, Garth
Ichhpujani, Parul
author_facet Katz, L. Jay
Stirbu, Oana
Willis, Garth
Ichhpujani, Parul
author_sort Katz, L. Jay
collection PubMed
description We present a 78-year-old patient who developed refractory glaucoma following a fungal infection of the corneal incision after cataract extraction with posterior chamber intraocular lens implantation. An anterior chamber injection of 0.1 ml recombinant tissue plasminogen activator (25 mcg/0.1 mL) was performed to improve the trabecular meshwork outflow facility compromised secondary to fibrin blockade. The intraocular pressure dropped dramatically from 48 mmHg to 10 mmHg postoperatively, negating the need for glaucoma surgery.
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spelling pubmed-27712692009-11-03 Intracameral Recombinant Tissue Plasminogen Activator for Refractory Glaucoma Secondary to a Fungal Corneal Abscess Katz, L. Jay Stirbu, Oana Willis, Garth Ichhpujani, Parul Open Ophthalmol J Article We present a 78-year-old patient who developed refractory glaucoma following a fungal infection of the corneal incision after cataract extraction with posterior chamber intraocular lens implantation. An anterior chamber injection of 0.1 ml recombinant tissue plasminogen activator (25 mcg/0.1 mL) was performed to improve the trabecular meshwork outflow facility compromised secondary to fibrin blockade. The intraocular pressure dropped dramatically from 48 mmHg to 10 mmHg postoperatively, negating the need for glaucoma surgery. Bentham Open 2009-09-25 /pmc/articles/PMC2771269/ /pubmed/19888435 http://dx.doi.org/10.2174/1874364100903010075 Text en © Katz et al Licensee Bentham Open. http://creativecommons.org/licenses/by-nc/3.0/ This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
spellingShingle Article
Katz, L. Jay
Stirbu, Oana
Willis, Garth
Ichhpujani, Parul
Intracameral Recombinant Tissue Plasminogen Activator for Refractory Glaucoma Secondary to a Fungal Corneal Abscess
title Intracameral Recombinant Tissue Plasminogen Activator for Refractory Glaucoma Secondary to a Fungal Corneal Abscess
title_full Intracameral Recombinant Tissue Plasminogen Activator for Refractory Glaucoma Secondary to a Fungal Corneal Abscess
title_fullStr Intracameral Recombinant Tissue Plasminogen Activator for Refractory Glaucoma Secondary to a Fungal Corneal Abscess
title_full_unstemmed Intracameral Recombinant Tissue Plasminogen Activator for Refractory Glaucoma Secondary to a Fungal Corneal Abscess
title_short Intracameral Recombinant Tissue Plasminogen Activator for Refractory Glaucoma Secondary to a Fungal Corneal Abscess
title_sort intracameral recombinant tissue plasminogen activator for refractory glaucoma secondary to a fungal corneal abscess
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771269/
https://www.ncbi.nlm.nih.gov/pubmed/19888435
http://dx.doi.org/10.2174/1874364100903010075
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