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Diminished Macrophage Apoptosis and Reactive Oxygen Species Generation after Phorbol Ester Stimulation in Crohn's Disease
BACKGROUND: Crohn's Disease (CD) is a chronic relapsing disorder characterized by granulomatous inflammation of the gastrointestinal tract. Although its pathogenesis is complex, we have recently shown that CD patients have a systemic defect in macrophage function, which results in the defective...
Autores principales: | Palmer, Christine D., Rahman, Farooq Z., Sewell, Gavin W., Ahmed, Afshan, Ashcroft, Margaret, Bloom, Stuart L., Segal, Anthony W., Smith, Andrew M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771353/ https://www.ncbi.nlm.nih.gov/pubmed/19907654 http://dx.doi.org/10.1371/journal.pone.0007787 |
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