Cargando…

Diminished Macrophage Apoptosis and Reactive Oxygen Species Generation after Phorbol Ester Stimulation in Crohn's Disease

BACKGROUND: Crohn's Disease (CD) is a chronic relapsing disorder characterized by granulomatous inflammation of the gastrointestinal tract. Although its pathogenesis is complex, we have recently shown that CD patients have a systemic defect in macrophage function, which results in the defective...

Descripción completa

Detalles Bibliográficos
Autores principales:	Palmer, Christine D., Rahman, Farooq Z., Sewell, Gavin W., Ahmed, Afshan, Ashcroft, Margaret, Bloom, Stuart L., Segal, Anthony W., Smith, Andrew M.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771353/ https://www.ncbi.nlm.nih.gov/pubmed/19907654 http://dx.doi.org/10.1371/journal.pone.0007787

Ejemplares similares

Defective tumor necrosis factor release from Crohn's disease macrophages in response to toll-like receptor activation: Relationship to phenotype and genome-wide association susceptibility loci
por: Sewell, Gavin W, et al.
Publicado: (2012)

Regulation of urokinase receptors in monocytelike U937 cells by phorbol ester phorbol myristate acetate
Publicado: (1989)

Antiallergic Phorbol Ester from the Seeds of Aquilaria malaccensis
por: Korinek, Michal, et al.
Publicado: (2016)

Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease
por: Smith, Andrew M., et al.
Publicado: (2009)

Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease
por: Smith, Andrew M., et al.
Publicado: (2009)

Role of Protein Kinase C and Nox2-Derived Reactive Oxygen Species Formation in the Activation and Maturation of Dendritic Cells by Phorbol Ester and Lipopolysaccharide
por: Stein, Judith, et al.
Publicado: (2017)

Cell surface dynamics of neutrophils stimulated with phorbol esters or retinoids
Publicado: (1987)

Lipidomic profiling in Crohn's disease: Abnormalities in phosphatidylinositols, with preservation of ceramide, phosphatidylcholine and phosphatidylserine composition
por: Sewell, Gavin W., et al.
Publicado: (2012)

Phorbol esters and horseradish peroxidase stimulate pinocytosis and redirect the flow of pinocytosed fluid in macrophages
Publicado: (1985)

THE TUMOR-PROMOTER PHORBOL ESTER (12-0-TETRADECANOYL-PHORBOL-13-ACETATE), A POTENT AGGREGATING AGENT FOR BLOOD PLATELETS
por: Zucker, Marjorie B., et al.
Publicado: (1974)

The peroxisome proliferator activated receptor δ is required for the differentiation of THP-1 monocytic cells by phorbol ester
por: Vosper, Helen, et al.
Publicado: (2003)

Regulation of agrin-induced acetylcholine receptor aggregation by Ca++ and phorbol ester
Publicado: (1988)

Phorbol ester degradation in Jatropha seedcake using white rot fungi
por: Bose, Anjali, et al.
Publicado: (2013)

The Trace Element Selenium Is Important for Redox Signaling in Phorbol Ester-Differentiated THP-1 Macrophages
por: Wolfram, Theresa, et al.
Publicado: (2021)

Phorbol ester-induced actin assembly in neutrophils: role of protein kinase C
Publicado: (1992)

Phorbol esters alter cell fate during development of sea urchin embryos
Publicado: (1992)

Phorbol ester modulation of integrin-mediated cell adhesion: a postreceptor event
Publicado: (1989)

Reorganization of alpha-actinin and vinculin induced by a phorbol ester in living cells
Publicado: (1986)

Phorbol ester induces elevated oxidative activity and alkalization in a subset of lysosomes
por: Chen, Chii-Shiarng
Publicado: (2002)

Analyzing phorbol ester effects on gap junctional communication: a dramatic inhibition of assembly
Publicado: (1994)

Cigarette smoke condensate attenuates phorbol ester-mediated neutrophil extracellular trap formation
por: Bokaba, Refilwe Philadelphia, et al.
Publicado: (2017)

Mapping of QTLs for Seed Phorbol Esters, a Toxic Chemical in Jatropha curcas (L.)
por: Amkul, Kitiya, et al.
Publicado: (2017)

The PMA Phorbol Ester Tumor Promoter Increases Canonical Wnt Signaling Via Macropinocytosis
por: Tejeda-Muñoz, Nydia, et al.
Publicado: (2023)

The PMA phorbol ester tumor promoter increases canonical Wnt signaling via macropinocytosis
por: Tejeda-Munoz, Nydia, et al.
Publicado: (2023)

Disruption of macrophage pro-inflammatory cytokine release in Crohn's disease is associated with reduced optineurin expression in a subset of patients
por: Smith, Andrew M, et al.
Publicado: (2015)

Phorbol Esters and SDF-1 Induce Rapid Endocytosis and Down Modulation of the Chemokine Receptor CXCR4
por: Signoret, Natalie, et al.
Publicado: (1997)

Phorbol ester treatment stimulates tyrosine phosphorylation of a sea urchin egg cortex protein
Publicado: (1990)

Early Induction of Cyclin D2 Expression in Phorbol Ester–responsive B-1 Lymphocytes
por: Tanguay, Debra A., et al.
Publicado: (1999)

The requirement for lymphocyte function-associated antigen 1 in homotypic leukocyte adhesion stimulated by phorbol ester
Publicado: (1986)

Abolished adherence alters signaling pathways in phorbol ester-induced human U937 cells
por: Otte, Anna, et al.
Publicado: (2011)

Phorbol esters and CAMP differentially regulate the expression of CD4 and CD8 in human thymocytes
por: Martinez-Valdez, Hector, et al.
Publicado: (2002)

Enhanced histamine production through the induction of histidine decarboxylase expression by phorbol ester in Jurkat cells
por: NAGASHIMA, YUSUKE, et al.
Publicado: (2012)

Phorbol Ester Modulation of Ca(2+) Channels Mediates Nociceptive Transmission in Dorsal Horn Neurones
por: Yang, Li, et al.
Publicado: (2013)

Transcription profile data of phorbol esters biosynthetic genes during developmental stages in Jatropha curcas
por: Jadid, Nurul, et al.
Publicado: (2018)

Tumor‐promoting Phorbol Ester Induces Alterations of Sialidase and Sialyltransferase Activities of JB6 Cells
por: Miyagi, Taeko, et al.
Publicado: (1990)

Hydroxy-octadecenoic acids instead of phorbol esters are responsible for the Jatropha curcas kernel cake’s toxicity
por: Wang, Xing-Hong, et al.
Publicado: (2020)

(+)-Borneol inhibits the generation of reactive oxygen species and neutrophil extracellular traps induced by phorbol-12-myristate-13-acetate
por: Chen, Hanze, et al.
Publicado: (2022)

Phorbol ester receptors and protein kinase C in primary neuronal cultures: development and stimulation of endogenous phosphorylation
Publicado: (1986)

Human tumor necrosis factor alpha gene regulation in phorbol ester stimulated T and B cell lines
Publicado: (1991)

Release of superoxide and change in morphology by neutrophils in response to phorbol esters: antagonism by inhibitors of calcium-binding proteins
Publicado: (1985)

Cannot write session to /tmp/vufind_sessions/sess_q7pvu8ot6jg7lm2sjembjrjqht