Stochastic Drift in Mitochondrial DNA Point Mutations: A Novel Perspective Ex Silico

The mitochondrial free radical theory of aging (mFRTA) implicates Reactive Oxygen Species (ROS)-induced mutations of mitochondrial DNA (mtDNA) as a major cause of aging. However, fifty years after its inception, several of its premises are intensely debated. Much of this uncertainty is due to the la...

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Detalles Bibliográficos
Autores principales: Poovathingal, Suresh Kumar, Gruber, Jan, Halliwell, Barry, Gunawan, Rudiyanto
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771766/
https://www.ncbi.nlm.nih.gov/pubmed/19936024
http://dx.doi.org/10.1371/journal.pcbi.1000572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771766/
https://www.ncbi.nlm.nih.gov/pubmed/19936024
http://dx.doi.org/10.1371/journal.pcbi.1000572

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