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Genetic Association Analysis of the Functional c.714T>G Polymorphism and Mucosal Expression of Dectin-1 in Inflammatory Bowel Disease

BACKGROUND: Dectin-1 is a pattern recognition receptor (PRR) expressed by myeloid cells that specifically recognizes β-1,3 glucan, a polysaccharide and major component of the fungal cell wall. Upon activation, dectin-1 signaling converges, similar to NOD2, on the adaptor molecule CARD9 which is asso...

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Detalles Bibliográficos
Autores principales:	de Vries, Hilbert S., Plantinga, Theo S., van Krieken, J. Han, Stienstra, Rinke, van Bodegraven, Ad A., Festen, Eleonora A. M., Weersma, Rinse K., Crusius, J. Bart A., Linskens, Ronald K., Joosten, Leo A. B., Netea, Mihai G., de Jong, Dirk J.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771910/ https://www.ncbi.nlm.nih.gov/pubmed/19915667 http://dx.doi.org/10.1371/journal.pone.0007818

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