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Experiences with carotid endarterectomy at Sree Chitra Tirunal Institute

BACKGROUND: Atherosclerotic carotid artery disease poses a grave threat to cerebral circulation, leading to a stroke with its devastating sequelae, if left untreated. Carotid endarterectomy has a proven track record with compelling evidence in stroke prevention. OBJECTIVES: a) To confirm that caroti...

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Autores principales: Unnikrishnan, Madathipat, Siddappa, Shivananda, Anto, Rajesh, Babu, Vivek, Paul, Benny, Kapilamoorthy, Thirur Raman, Sivasankaran, Sivasubramanian, Sandhyamani, Samavedam, Sreedhar, Rupa, Radhakrishnan, Kuruppath
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771972/
https://www.ncbi.nlm.nih.gov/pubmed/19893664
http://dx.doi.org/10.4103/0972-2327.42937
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author Unnikrishnan, Madathipat
Siddappa, Shivananda
Anto, Rajesh
Babu, Vivek
Paul, Benny
Kapilamoorthy, Thirur Raman
Sivasankaran, Sivasubramanian
Sandhyamani, Samavedam
Sreedhar, Rupa
Radhakrishnan, Kuruppath
author_facet Unnikrishnan, Madathipat
Siddappa, Shivananda
Anto, Rajesh
Babu, Vivek
Paul, Benny
Kapilamoorthy, Thirur Raman
Sivasankaran, Sivasubramanian
Sandhyamani, Samavedam
Sreedhar, Rupa
Radhakrishnan, Kuruppath
author_sort Unnikrishnan, Madathipat
collection PubMed
description BACKGROUND: Atherosclerotic carotid artery disease poses a grave threat to cerebral circulation, leading to a stroke with its devastating sequelae, if left untreated. Carotid endarterectomy has a proven track record with compelling evidence in stroke prevention. OBJECTIVES: a) To confirm that carotid endarterectomy (CEA) is safe and effective in preventing stroke at both short and long term. b) to demonstrate long term patency of internal carotid artery when arteriotomy repair is performed using autologous saphenous vein patch. MATERIALS AND METHODS: During ten years, from September 1997 to February 2008, thirty nine patients who underwent consecutive carotid endarterectomy at our institute, form the basis of this report. Their age ranged from thirty to seventy eight years, with a mean age of 56. There were four women in this cohort. Thirty seven patients were symptomatic with >70% stenosis and two were asymptomatic with >80% stenosis, incidentally detected. Imaging included Duplex scan and MRA for carotid territory and brain, and non-invasive cardiac assessment. Co-morbidities included smoking, hypertension, diabetes, and coronary artery disease. Carotid Endarterectomy was performed under general anaesthesia, using carotid shunt and vein patch arteriotomy repair. RESULTS: All the patients made satisfactory recovery, without major adverse cerebral events in this series. Morbidities included Transient Ischemic Attack (TIA) in two, needing only medications in one, and carotid stenting in the other. Minor morbidities included neck hematoma in two and transient hypoglossal paresis in three patients. Yearly follow-up included duplex scan assessment for all the patients. Two patients died of contralateral stroke, two of myocardial events and two were lost to follow up. Thirty three patients are well and free of the disease during the follow up of three to 120 months. CONCLUSION: Carotid endarterectomy provided near total freedom from adverse cerebral events and its catastrophic sequelae, leading to excellent outcome, both short as well as long term.
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spelling pubmed-27719722009-11-05 Experiences with carotid endarterectomy at Sree Chitra Tirunal Institute Unnikrishnan, Madathipat Siddappa, Shivananda Anto, Rajesh Babu, Vivek Paul, Benny Kapilamoorthy, Thirur Raman Sivasankaran, Sivasubramanian Sandhyamani, Samavedam Sreedhar, Rupa Radhakrishnan, Kuruppath Ann Indian Acad Neurol Original Article BACKGROUND: Atherosclerotic carotid artery disease poses a grave threat to cerebral circulation, leading to a stroke with its devastating sequelae, if left untreated. Carotid endarterectomy has a proven track record with compelling evidence in stroke prevention. OBJECTIVES: a) To confirm that carotid endarterectomy (CEA) is safe and effective in preventing stroke at both short and long term. b) to demonstrate long term patency of internal carotid artery when arteriotomy repair is performed using autologous saphenous vein patch. MATERIALS AND METHODS: During ten years, from September 1997 to February 2008, thirty nine patients who underwent consecutive carotid endarterectomy at our institute, form the basis of this report. Their age ranged from thirty to seventy eight years, with a mean age of 56. There were four women in this cohort. Thirty seven patients were symptomatic with >70% stenosis and two were asymptomatic with >80% stenosis, incidentally detected. Imaging included Duplex scan and MRA for carotid territory and brain, and non-invasive cardiac assessment. Co-morbidities included smoking, hypertension, diabetes, and coronary artery disease. Carotid Endarterectomy was performed under general anaesthesia, using carotid shunt and vein patch arteriotomy repair. RESULTS: All the patients made satisfactory recovery, without major adverse cerebral events in this series. Morbidities included Transient Ischemic Attack (TIA) in two, needing only medications in one, and carotid stenting in the other. Minor morbidities included neck hematoma in two and transient hypoglossal paresis in three patients. Yearly follow-up included duplex scan assessment for all the patients. Two patients died of contralateral stroke, two of myocardial events and two were lost to follow up. Thirty three patients are well and free of the disease during the follow up of three to 120 months. CONCLUSION: Carotid endarterectomy provided near total freedom from adverse cerebral events and its catastrophic sequelae, leading to excellent outcome, both short as well as long term. Medknow Publications 2008 /pmc/articles/PMC2771972/ /pubmed/19893664 http://dx.doi.org/10.4103/0972-2327.42937 Text en © Annals of Indian Academy of Neurology http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Unnikrishnan, Madathipat
Siddappa, Shivananda
Anto, Rajesh
Babu, Vivek
Paul, Benny
Kapilamoorthy, Thirur Raman
Sivasankaran, Sivasubramanian
Sandhyamani, Samavedam
Sreedhar, Rupa
Radhakrishnan, Kuruppath
Experiences with carotid endarterectomy at Sree Chitra Tirunal Institute
title Experiences with carotid endarterectomy at Sree Chitra Tirunal Institute
title_full Experiences with carotid endarterectomy at Sree Chitra Tirunal Institute
title_fullStr Experiences with carotid endarterectomy at Sree Chitra Tirunal Institute
title_full_unstemmed Experiences with carotid endarterectomy at Sree Chitra Tirunal Institute
title_short Experiences with carotid endarterectomy at Sree Chitra Tirunal Institute
title_sort experiences with carotid endarterectomy at sree chitra tirunal institute
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771972/
https://www.ncbi.nlm.nih.gov/pubmed/19893664
http://dx.doi.org/10.4103/0972-2327.42937
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