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Meningitis caused by Rhodotorula mucilaginosa in human immunodeficiency virus seropositive patient

Rhodotorula species may be responsible for systemic infection in immunocompromised patients. Meningitis by Rhodotorula species in human immunodeficiency virus (HIV) infected persons has been reported previously. We report a case of meningitis caused by Rhodotorula mucilaginosa in a 36-year-old HIV s...

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Detalles Bibliográficos
Autores principales: Baradkar, V. P., Kumar, S.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771990/
https://www.ncbi.nlm.nih.gov/pubmed/19893682
http://dx.doi.org/10.4103/0972-2327.44561
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author Baradkar, V. P.
Kumar, S.
author_facet Baradkar, V. P.
Kumar, S.
author_sort Baradkar, V. P.
collection PubMed
description Rhodotorula species may be responsible for systemic infection in immunocompromised patients. Meningitis by Rhodotorula species in human immunodeficiency virus (HIV) infected persons has been reported previously. We report a case of meningitis caused by Rhodotorula mucilaginosa in a 36-year-old HIV seropositive male patient who presented with fever, altered sensorium and features of meningeal irritation i.e. neck rigidity. The Cerebrospinal fluid (CSF) cell counts were high, showing 150 cells/mm(3), with 60% lymphocytes and 40% polymorphs, and protein content of 100 mg%; glucose was 60 mg%. The diagnosis was confirmed by culture on Sabouraud's Dextrose agar. The patient was treated successfully with intensive Amphotericin B (1 mg/kg), for two weeks, followed by oral Itraconazole (400 mg daily), for a period of two months. The patient was started on anti retroviral therapy. He did not show any relapse of the symptoms when the last follow up was done six months after the date of discharge.
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spelling pubmed-27719902009-11-05 Meningitis caused by Rhodotorula mucilaginosa in human immunodeficiency virus seropositive patient Baradkar, V. P. Kumar, S. Ann Indian Acad Neurol Case Report Rhodotorula species may be responsible for systemic infection in immunocompromised patients. Meningitis by Rhodotorula species in human immunodeficiency virus (HIV) infected persons has been reported previously. We report a case of meningitis caused by Rhodotorula mucilaginosa in a 36-year-old HIV seropositive male patient who presented with fever, altered sensorium and features of meningeal irritation i.e. neck rigidity. The Cerebrospinal fluid (CSF) cell counts were high, showing 150 cells/mm(3), with 60% lymphocytes and 40% polymorphs, and protein content of 100 mg%; glucose was 60 mg%. The diagnosis was confirmed by culture on Sabouraud's Dextrose agar. The patient was treated successfully with intensive Amphotericin B (1 mg/kg), for two weeks, followed by oral Itraconazole (400 mg daily), for a period of two months. The patient was started on anti retroviral therapy. He did not show any relapse of the symptoms when the last follow up was done six months after the date of discharge. Medknow Publications 2008 /pmc/articles/PMC2771990/ /pubmed/19893682 http://dx.doi.org/10.4103/0972-2327.44561 Text en © Annals of Indian Academy of Neurology http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Baradkar, V. P.
Kumar, S.
Meningitis caused by Rhodotorula mucilaginosa in human immunodeficiency virus seropositive patient
title Meningitis caused by Rhodotorula mucilaginosa in human immunodeficiency virus seropositive patient
title_full Meningitis caused by Rhodotorula mucilaginosa in human immunodeficiency virus seropositive patient
title_fullStr Meningitis caused by Rhodotorula mucilaginosa in human immunodeficiency virus seropositive patient
title_full_unstemmed Meningitis caused by Rhodotorula mucilaginosa in human immunodeficiency virus seropositive patient
title_short Meningitis caused by Rhodotorula mucilaginosa in human immunodeficiency virus seropositive patient
title_sort meningitis caused by rhodotorula mucilaginosa in human immunodeficiency virus seropositive patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771990/
https://www.ncbi.nlm.nih.gov/pubmed/19893682
http://dx.doi.org/10.4103/0972-2327.44561
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