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Aluminum phosphide poisoning: Effect of correction of severe metabolic acidosis on patient outcome

Forty patients of aluminum phosphide poisoning who were admitted to the ICU of Sir Sunder Lal Hospital, Banaras Hindu University, were studied. Restlessness, excessive thirst, shock, arrhythmias, tachypnoea, and severe metabolic acidosis were the common clinical findings. Only repeated and full corr...

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Autores principales: Jaiswal, S., Verma, R. K., Tewari, N.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2772262/
https://www.ncbi.nlm.nih.gov/pubmed/19881175
http://dx.doi.org/10.4103/0972-5229.53111
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author Jaiswal, S.
Verma, R. K.
Tewari, N.
author_facet Jaiswal, S.
Verma, R. K.
Tewari, N.
author_sort Jaiswal, S.
collection PubMed
description Forty patients of aluminum phosphide poisoning who were admitted to the ICU of Sir Sunder Lal Hospital, Banaras Hindu University, were studied. Restlessness, excessive thirst, shock, arrhythmias, tachypnoea, and severe metabolic acidosis were the common clinical findings. Only repeated and full correction with intravenous sodium bicarbonate was able to cope up with the severity and rapidity of acidosis. There was no significant change in blood pressure, pulse rate, and respiratory rate after full correction but gradually pulse and systolic blood pressure settled after ionotropic support in the survivors. There was significant improvement from 30.36% in the case when only half correction was done, as has been the common practice, to 57.5%, when full correction of metabolic acidosis was done.
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spelling pubmed-27722622009-11-05 Aluminum phosphide poisoning: Effect of correction of severe metabolic acidosis on patient outcome Jaiswal, S. Verma, R. K. Tewari, N. Indian J Crit Care Med Research Article Forty patients of aluminum phosphide poisoning who were admitted to the ICU of Sir Sunder Lal Hospital, Banaras Hindu University, were studied. Restlessness, excessive thirst, shock, arrhythmias, tachypnoea, and severe metabolic acidosis were the common clinical findings. Only repeated and full correction with intravenous sodium bicarbonate was able to cope up with the severity and rapidity of acidosis. There was no significant change in blood pressure, pulse rate, and respiratory rate after full correction but gradually pulse and systolic blood pressure settled after ionotropic support in the survivors. There was significant improvement from 30.36% in the case when only half correction was done, as has been the common practice, to 57.5%, when full correction of metabolic acidosis was done. Medknow Publications 2009 /pmc/articles/PMC2772262/ /pubmed/19881175 http://dx.doi.org/10.4103/0972-5229.53111 Text en © Indian Journal of Critical Care Medicine http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Jaiswal, S.
Verma, R. K.
Tewari, N.
Aluminum phosphide poisoning: Effect of correction of severe metabolic acidosis on patient outcome
title Aluminum phosphide poisoning: Effect of correction of severe metabolic acidosis on patient outcome
title_full Aluminum phosphide poisoning: Effect of correction of severe metabolic acidosis on patient outcome
title_fullStr Aluminum phosphide poisoning: Effect of correction of severe metabolic acidosis on patient outcome
title_full_unstemmed Aluminum phosphide poisoning: Effect of correction of severe metabolic acidosis on patient outcome
title_short Aluminum phosphide poisoning: Effect of correction of severe metabolic acidosis on patient outcome
title_sort aluminum phosphide poisoning: effect of correction of severe metabolic acidosis on patient outcome
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2772262/
https://www.ncbi.nlm.nih.gov/pubmed/19881175
http://dx.doi.org/10.4103/0972-5229.53111
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