Combined treatment with lexatumumab and irradiation leads to strongly increased long term tumour control under normoxic and hypoxic conditions

PURPOSE: The combination of ionizing radiation with the pro-apoptotic TRAIL receptor antibody lexatumumab has been shown to exert considerable synergistic apoptotic effects in vitro and in short term growth delay assays. To clarify the relevance of these effects on local tumour control long-term exp...

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Detalles Bibliográficos
Autores principales: Marini, Patrizia, Junginger, Dorothea, Stickl, Stefan, Budach, Wilfried, Niyazi, Maximilian, Belka, Claus
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2772841/
https://www.ncbi.nlm.nih.gov/pubmed/19860913
http://dx.doi.org/10.1186/1748-717X-4-49

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