Persistence Criteria for Susceptibility Genes for Schizophrenia: a Discussion from an Evolutionary Viewpoint

BACKGROUND: The central paradox of schizophrenia genetics is that susceptibility genes are preserved in the human gene-pool against a strong negative selection pressure. Substantial evidence of epidemiology suggests that nuclear susceptibility genes, if present, should be sustained by mutation-selec...

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Detalles Bibliográficos
Autores principales: Doi, Nagafumi, Hoshi, Yoko, Itokawa, Masanari, Usui, Chie, Yoshikawa, Takeo, Tachikawa, Hirokazu
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2772980/
https://www.ncbi.nlm.nih.gov/pubmed/19911060
http://dx.doi.org/10.1371/journal.pone.0007799

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