Immunopurification of Pathological Prion Protein Aggregates

BACKGROUND: Prion diseases are fatal neurodegenerative disorders that can arise sporadically, be genetically inherited or acquired through infection. The key event in these diseases is misfolding of the cellular prion protein (PrP(C)) into a pathogenic isoform that is rich in β-sheet structure. This...

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Detalles Bibliográficos
Autores principales: Biasini, Emiliano, Tapella, Laura, Mantovani, Susanna, Stravalaci, Matteo, Gobbi, Marco, Harris, David A., Chiesa, Roberto
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773113/
https://www.ncbi.nlm.nih.gov/pubmed/19915706
http://dx.doi.org/10.1371/journal.pone.0007816

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773113/
https://www.ncbi.nlm.nih.gov/pubmed/19915706
http://dx.doi.org/10.1371/journal.pone.0007816

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