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Reversing Blood Flows Act through klf2a to Ensure Normal Valvulogenesis in the Developing Heart

Heart valve anomalies are some of the most common congenital heart defects, yet neither the genetic nor the epigenetic forces guiding heart valve development are well understood. When functioning normally, mature heart valves prevent intracardiac retrograde blood flow; before valves develop, there i...

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Detalles Bibliográficos
Autores principales: Vermot, Julien, Forouhar, Arian S., Liebling, Michael, Wu, David, Plummer, Diane, Gharib, Morteza, Fraser, Scott E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773122/
https://www.ncbi.nlm.nih.gov/pubmed/19924233
http://dx.doi.org/10.1371/journal.pbio.1000246