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Methyl-CpG-Binding PCR of Bloodspots for Confirmation of Fragile X Syndrome in Males

This study demonstrates that methyl-CpG-binding PCR (MB-PCR) is a rapid and simple method for detecting fragile X syndrome (FXS) in males, which is performed by verifying the methylation status of the FMR1 promoter in bloodspots. Proteins containing methyl-CpG-binding (MB) domains can be freeze-stor...

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Detalles Bibliográficos
Autores principales:	Tzeng, Ching-Cherng, Liou, Chiou-Ping, Li, Chien-Feng, Lai, Ming-Chi, Tsai, Li-Ping, Cho, Wei-Chen, Chang, Hui-Ting
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2009
Materias:	Methodology Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773378/ https://www.ncbi.nlm.nih.gov/pubmed/19893637 http://dx.doi.org/10.1155/2009/643692

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