Latest advances in innate antiviral defence

Recent identification of key components in the pattern recognition receptor pathway of retinoic acid-inducible gene-1-like receptors, coupled with the characterisation of a new cytoplasmic DNA-sensing molecule, has led to a greater understanding of the role that viral nucleic acids play in activatin...

Descripción completa

Detalles Bibliográficos
Autores principales: Irving, Aaron, Williams, Bryan RG
Formato: Texto
Lenguaje:English
Publicado: Biology Reports Ltd 2009
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773505/
https://www.ncbi.nlm.nih.gov/pubmed/20160888
http://dx.doi.org/10.3410/B1-22
_version_ 1782173871875555328
author Irving, Aaron
Williams, Bryan RG
author_facet Irving, Aaron
Williams, Bryan RG
author_sort Irving, Aaron
collection PubMed
description Recent identification of key components in the pattern recognition receptor pathway of retinoic acid-inducible gene-1-like receptors, coupled with the characterisation of a new cytoplasmic DNA-sensing molecule, has led to a greater understanding of the role that viral nucleic acids play in activating innate immunity. This activation of type-I interferon is essential for both limiting viral infection and stimulating activation of the adaptive immune response.
format Text
id pubmed-2773505
institution National Center for Biotechnology Information
language English
publishDate 2009
publisher Biology Reports Ltd
record_format MEDLINE/PubMed
spelling pubmed-27735052010-03-17 Latest advances in innate antiviral defence Irving, Aaron Williams, Bryan RG F1000 Biol Rep Review Article Recent identification of key components in the pattern recognition receptor pathway of retinoic acid-inducible gene-1-like receptors, coupled with the characterisation of a new cytoplasmic DNA-sensing molecule, has led to a greater understanding of the role that viral nucleic acids play in activating innate immunity. This activation of type-I interferon is essential for both limiting viral infection and stimulating activation of the adaptive immune response. Biology Reports Ltd 2009-03-17 /pmc/articles/PMC2773505/ /pubmed/20160888 http://dx.doi.org/10.3410/B1-22 Text en © 2009 Biology Reports Ltd http://creativecommons.org/licenses/by-nc/3.0/legalcode This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes
spellingShingle Review Article
Irving, Aaron
Williams, Bryan RG
Latest advances in innate antiviral defence
title Latest advances in innate antiviral defence
title_full Latest advances in innate antiviral defence
title_fullStr Latest advances in innate antiviral defence
title_full_unstemmed Latest advances in innate antiviral defence
title_short Latest advances in innate antiviral defence
title_sort latest advances in innate antiviral defence
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773505/
https://www.ncbi.nlm.nih.gov/pubmed/20160888
http://dx.doi.org/10.3410/B1-22
work_keys_str_mv AT irvingaaron latestadvancesininnateantiviraldefence
AT williamsbryanrg latestadvancesininnateantiviraldefence

Ejemplares similares