Effects of 4-Aminopyridine on Cloned hERG Channels Expressed in Mammalian Cells

INTRODUCTION: Non-clinical evaluation of a medication's potential to induce cardiac toxicity is recommended by regulatory agencies. 4-Aminopyridine (fampridine) is a potassium channel blocker with the demonstrated ability to improve walking ability in patients with multiple sclerosis. We evalua...

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Detalles Bibliográficos
Autores principales: Renganathan, Muthukrishnan, Sidach, Serguei, Blight, Andrew R
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Inc 2009
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773527/
https://www.ncbi.nlm.nih.gov/pubmed/19915712
http://dx.doi.org/10.1111/j.1753-5174.2009.00021.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773527/
https://www.ncbi.nlm.nih.gov/pubmed/19915712
http://dx.doi.org/10.1111/j.1753-5174.2009.00021.x

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