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Effects of 4-Aminopyridine on Cloned hERG Channels Expressed in Mammalian Cells
INTRODUCTION: Non-clinical evaluation of a medication's potential to induce cardiac toxicity is recommended by regulatory agencies. 4-Aminopyridine (fampridine) is a potassium channel blocker with the demonstrated ability to improve walking ability in patients with multiple sclerosis. We evalua...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Inc
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773527/ https://www.ncbi.nlm.nih.gov/pubmed/19915712 http://dx.doi.org/10.1111/j.1753-5174.2009.00021.x |