Personalizing Drug Selection Using Advanced Clinical Decision Support

This article describes the process of developing an advanced pharmacogenetics clinical decision support at one of the United States’ leading pediatric academic medical centers. This system, called CHRISTINE, combines clinical and genetic data to identify the optimal drug therapy when treating patien...

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Detalles Bibliográficos
Autores principales: Pestian, John, Spencer, Malik, Matykiewicz, Pawel, Zhang, Kejian, Vinks, Sander, Glauser, Tracy
Formato: Texto
Lenguaje:English
Publicado: SAGE Publications 2009
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773552/
https://www.ncbi.nlm.nih.gov/pubmed/19898682
http://dx.doi.org/10.4137/BII.S2506
Descripción
Sumario:This article describes the process of developing an advanced pharmacogenetics clinical decision support at one of the United States’ leading pediatric academic medical centers. This system, called CHRISTINE, combines clinical and genetic data to identify the optimal drug therapy when treating patients with epilepsy or Attention Deficit Hyperactivity Disorder. In the discussion a description of clinical decision support systems is provided, along with an overview of neurocognitive computing and how it is applied in this setting.

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