Personalizing Drug Selection Using Advanced Clinical Decision Support

This article describes the process of developing an advanced pharmacogenetics clinical decision support at one of the United States’ leading pediatric academic medical centers. This system, called CHRISTINE, combines clinical and genetic data to identify the optimal drug therapy when treating patien...

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Autores principales: Pestian, John, Spencer, Malik, Matykiewicz, Pawel, Zhang, Kejian, Vinks, Sander, Glauser, Tracy
Formato: Texto
Lenguaje:English
Publicado: SAGE Publications 2009
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773552/
https://www.ncbi.nlm.nih.gov/pubmed/19898682
http://dx.doi.org/10.4137/BII.S2506
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author Pestian, John
Spencer, Malik
Matykiewicz, Pawel
Zhang, Kejian
Vinks, Sander
Glauser, Tracy
author_facet Pestian, John
Spencer, Malik
Matykiewicz, Pawel
Zhang, Kejian
Vinks, Sander
Glauser, Tracy
author_sort Pestian, John
collection PubMed
description This article describes the process of developing an advanced pharmacogenetics clinical decision support at one of the United States’ leading pediatric academic medical centers. This system, called CHRISTINE, combines clinical and genetic data to identify the optimal drug therapy when treating patients with epilepsy or Attention Deficit Hyperactivity Disorder. In the discussion a description of clinical decision support systems is provided, along with an overview of neurocognitive computing and how it is applied in this setting.
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spelling pubmed-27735522009-11-05 Personalizing Drug Selection Using Advanced Clinical Decision Support Pestian, John Spencer, Malik Matykiewicz, Pawel Zhang, Kejian Vinks, Sander Glauser, Tracy Biomed Inform Insights Case Report This article describes the process of developing an advanced pharmacogenetics clinical decision support at one of the United States’ leading pediatric academic medical centers. This system, called CHRISTINE, combines clinical and genetic data to identify the optimal drug therapy when treating patients with epilepsy or Attention Deficit Hyperactivity Disorder. In the discussion a description of clinical decision support systems is provided, along with an overview of neurocognitive computing and how it is applied in this setting. SAGE Publications 2009-06-23 /pmc/articles/PMC2773552/ /pubmed/19898682 http://dx.doi.org/10.4137/BII.S2506 Text en © 2009 SAGE Publications. http://creativecommons.org/licenses/by/2.0/ This article is distributed under the terms of the Creative Commons Attribution 2.0 License (http://www.creativecommons.org/licenses/by/2.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Pestian, John
Spencer, Malik
Matykiewicz, Pawel
Zhang, Kejian
Vinks, Sander
Glauser, Tracy
Personalizing Drug Selection Using Advanced Clinical Decision Support
title Personalizing Drug Selection Using Advanced Clinical Decision Support
title_full Personalizing Drug Selection Using Advanced Clinical Decision Support
title_fullStr Personalizing Drug Selection Using Advanced Clinical Decision Support
title_full_unstemmed Personalizing Drug Selection Using Advanced Clinical Decision Support
title_short Personalizing Drug Selection Using Advanced Clinical Decision Support
title_sort personalizing drug selection using advanced clinical decision support
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773552/
https://www.ncbi.nlm.nih.gov/pubmed/19898682
http://dx.doi.org/10.4137/BII.S2506
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AT zhangkejian personalizingdrugselectionusingadvancedclinicaldecisionsupport
AT vinkssander personalizingdrugselectionusingadvancedclinicaldecisionsupport
AT glausertracy personalizingdrugselectionusingadvancedclinicaldecisionsupport

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