iTRAQ-based Proteomics Profiling Reveals Increased Metabolic Activity and Cellular Cross-talk in Angiogenic Compared with Invasive Glioblastoma Phenotype

Malignant gliomas (glioblastoma multiforme) have a poor prognosis with an average patient survival under current treatment regimens ranging between 12 and 14 months. The tumors are characterized by rapid cell growth, extensive neovascularization, and diffuse cellular infiltration of normal brain str...

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Detalles Bibliográficos
Autores principales: Rajcevic, Uros, Petersen, Kjell, Knol, Jaco C., Loos, Maarten, Bougnaud, Sébastien, Klychnikov, Oleg, Li, Ka Wan, Pham, Thang V., Wang, Jian, Miletic, Hrvoje, Peng, Zhao, Bjerkvig, Rolf, Jimenez, Connie R., Niclou, Simone P.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773724/
https://www.ncbi.nlm.nih.gov/pubmed/19674965
http://dx.doi.org/10.1074/mcp.M900124-MCP200

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