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TGF-β inhibits IL-1β-activated PAR-2 expression through multiple pathways in human primary synovial cells
To investigate the mechanism how Transforming growth factor-β(TGF-β) represses Interleukin-1β (IL-1β)-induced Proteinase-Activated Receptor-2 (PAR-2) expression in human primary synovial cells (hPSCs). Human chondrocytes and hPSCs isolated from cartilages and synovium of Osteoarthritis (OA) patients...
Autores principales: | Tsai, Shin-Han, Sheu, Ming-Thau, Liang, Yu-Chih, Cheng, Hsiu-Tan, Fang, Sheng-Shiung, Chen, Chien-Ho |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773761/ https://www.ncbi.nlm.nih.gov/pubmed/19852794 http://dx.doi.org/10.1186/1423-0127-16-97 |
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