Dual effect of a single nucleotide polymorphism in the first intron of the porcine Secreted phosphoprotein 1 gene: allele-specific binding of C/EBP beta and activation of aberrant splicing

BACKGROUND: Secreted phosphoprotein 1 (SPP1 or Osteopontin, OPN) is a multifunctional matricellular glycoprotein involved in development and regeneration of skeletal muscle. Previously, we have demonstrated that porcine SPP1 shows breed-related differential mRNA expression during myogenesis. With th...

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Detalles Bibliográficos
Autores principales: Muráni, Eduard, Ponsuksili, Siriluck, Seyfert, Hans-Martin, Shi, Xuanming, Wimmers, Klaus
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773772/
https://www.ncbi.nlm.nih.gov/pubmed/19845957
http://dx.doi.org/10.1186/1471-2199-10-96

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773772/
https://www.ncbi.nlm.nih.gov/pubmed/19845957
http://dx.doi.org/10.1186/1471-2199-10-96

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