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Smad4-dependent pathways control basement membrane deposition and endodermal cell migration at early stages of mouse development
BACKGROUND: Smad4 mutant embryos arrest shortly after implantation and display a characteristic shortened proximodistal axis, a significantly reduced epiblast, as well as a thickened visceral endoderm layer. Conditional rescue experiments demonstrate that bypassing the primary requirement for Smad4...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773778/ https://www.ncbi.nlm.nih.gov/pubmed/19849841 http://dx.doi.org/10.1186/1471-213X-9-54 |