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TIde: a software for the systematic scanning of drug targets in kinetic network models

BACKGROUND: During the stages of the development of a potent drug candidate compounds can fail for several reasons. One of them, the efficacy of a candidate, can be estimated in silico if an appropriate ordinary differential equation model of the affected pathway is available. With such a model at h...

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Detalles Bibliográficos
Autores principales: Schulz, Marvin, Bakker, Barbara M, Klipp, Edda
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773792/
https://www.ncbi.nlm.nih.gov/pubmed/19840374
http://dx.doi.org/10.1186/1471-2105-10-344