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Biosynthesis of the proteasome inhibitor syringolin A: the ureido group joining two amino acids originates from bicarbonate

BACKGROUND: Syringolin A, an important virulence factor in the interaction of the phytopathogenic bacterium Pseudomonas syringae pv. syringae B728a with its host plant Phaseolus vulgaris (bean), was recently shown to irreversibly inhibit eukaryotic proteasomes by a novel mechanism. Syringolin A is s...

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Detalles Bibliográficos
Autores principales: Ramel, Christina, Tobler, Micha, Meyer, Martin, Bigler, Laurent, Ebert, Marc-Olivier, Schellenberg, Barbara, Dudler, Robert
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773804/
https://www.ncbi.nlm.nih.gov/pubmed/19863801
http://dx.doi.org/10.1186/1471-2091-10-26

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