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Biosynthesis of the proteasome inhibitor syringolin A: the ureido group joining two amino acids originates from bicarbonate
BACKGROUND: Syringolin A, an important virulence factor in the interaction of the phytopathogenic bacterium Pseudomonas syringae pv. syringae B728a with its host plant Phaseolus vulgaris (bean), was recently shown to irreversibly inhibit eukaryotic proteasomes by a novel mechanism. Syringolin A is s...
Autores principales: | Ramel, Christina, Tobler, Micha, Meyer, Martin, Bigler, Laurent, Ebert, Marc-Olivier, Schellenberg, Barbara, Dudler, Robert |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773804/ https://www.ncbi.nlm.nih.gov/pubmed/19863801 http://dx.doi.org/10.1186/1471-2091-10-26 |
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